The Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease study aims to research how exercise affects women with CAD. Subjects will be monitored after walking on a treadmill at a slow pace for 47 minutes.
In the study, subjects will be measured for dilation, arterial stiffness, and wave reflection to see if walking on a treadmill for 47 minutes at a slow pace affects them. The measurements will be done with brachial artery flow-mediated dilation via high resolution ultrasonography, sublingual nitroglycerin, and applanation tonometry. This is an interventional clinical trial with an estimated 75 participants in a single group assignment.
- Women with non-obstructive coronary artery disease documented by coronary angiogram
- Ages 18-89
- Use of tobacco products
- Use of oral contraceptives or hormone replacement therapy
- Pregnancy (positive urine pregnancy test) or lactation
- History of hepatic disease or infection with hepatitis B, C or HIV
Integrative Cardiovascular Physiology Laboratory
Gainesville, Florida, United States, 32611
Contact: Demetra Christou, PhD 352-294-1746 ICPL@hhp.ufl.edu
University of Florida
Principal Investigator: Demetra Christou, PhD, University of Florida
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